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IMAGE: From left to right: Mercè Masana, Ana Gámez-Valero, Eulàlia Martí, Anna Guisado-Corcoll, Esther Pérez-Navarro and Maria Solaguren-Beascoa. view more
Credit: UNIVERSITY OF BARCELONA
Huntington s disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations. The origin of this disease has been associated with the anomalous functioning of the mutated protein: mHTT, but recent data showed the involvement of other molecular mechanisms.
A new study conducted by the University of Barcelona has identified a type of ribonucleic acid (RNA) as a potential therapeutic target for the treatment of the disease. These are the small RNA, or sRNAs, molecules that do not code proteins but have important functions in the regulation of gene expression. According to the study, sRNAs would take part in the development of the disease, results that shed light on the design of new specific dr
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IMAGE: Dr. Omar Albagha, one of the principal investigators of Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits , Nature Communications 2021 view more
Credit: Qatar Foundation
Doha, Qatar - (February 23, 2021) - A group of researchers at Qatar Foundation have reported the first and largest genetic association study in the Middle East, that has been published online in
Nature Communications - a leading a peer-reviewed, open access, scientific journal published by Nature Research.
The study titled Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits highlights a vital piece of information wherein now there is a better understanding of the genetic risk factors that are specific to the Arab population, including those that are shared with other ethnicities.
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IMAGE: Evan Y. Snyder, M.D., Ph.D., professor and founding director of the Center for Stem Cells and Regenerative Medicine at Sanford Burnham Prebys Medical Discovery Institute. view more
Credit: Sanford Burnham Prebys Medical Discovery Institute
LA JOLLA, CALIF. - Feb. 23, 2021 - The American Institute for Medical and Biological Engineering (AIMBE) has elected to its College of Fellows Evan Y. Snyder, M.D., Ph.D., professor and founding director of the Center for Stem Cells and Regenerative Medicine at Sanford Burnham Prebys Medical Discovery Institute. Snyder was nominated, reviewed, and elected by his peers and members of the College of Fellows for his seminal contributions to regenerative medicine. He will be inducted to AIMBE during a formal ceremony held on March 26, 2021.
More than two-thirds of people with migraine do not get enough exercise, according to a preliminary study released today, February 23, 2021, that will be presented at the American Academy of Neurology s 73rd Annual Meeting being held virtually April 17 to 22, 2021.
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IMAGE: Brain opioid receptors measured with positron emission tomography (A) and regions, where opioid receptor density varied seasonally. view more
Credit: University of Turku
Seasons have an impact on our emotions and social life. Negative emotions are more subdued in the summer, whereas seasonal affective disorder rates peak during the darker winter months. Opioids regulate both mood and sociability in the brain.
In the study conducted at the Turku PET Centre, Finland, researchers compared how the length of daylight hours affected the opioid receptors in humans and rats. In the study, we observed that the number of opioid receptors was dependent on the time of the year the brain was imaged. The changes were most prominent in the brain regions that control emotions and sociability. The changes in the opioid receptors caused by the variation in the amount of daylight could be an important factor in seasonal affective disorder, says Postdoctoral Resear